发明名称 Feline rhinotracheitis vaccine - by attenuation of live virus by serial passage at 25 degree C in cat kidney cells
摘要 <p>The attenuated, antigenic cat herpes virus (a) virulent live herpes virus is introduced into a tissue culture, (b) the culture is incubated until evidence of cellular cytophatology is apparent, (c) the virus is collected and introduced into a new tissue culture, (d) serial passage of the virus, in tissue culture is conducted a sufficient number of times at an incubation temp. sufficient to produce a non-virulent live antigenic virus, (e) the attenuated virus is siolated. Used in the treatment and prevention of viral rhinotracheitis in cats which is specific for deoxyribonucleic acid of cats. Young cats may be inoculated with vaccine prepd. from an attenuated virus, either by intraocular or intra-auricular admin. while matl. antibody is still present.</p>
申请公布号 FR2327799(A1) 申请公布日期 1977.05.13
申请号 FR19750031873 申请日期 1975.10.17
申请人 PHILIPS GLOEILAMPENFABRIEKEN NV 发明人
分类号 A61K39/265;C12N7/08;(IPC1-7):61K39/12;12K5/00 主分类号 A61K39/265
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