摘要 |
<p>Title cpds. of formula (I): where R = H or lower alkyl, R' = H or lower alkyl, X = hal, OH or an ester residue, Y = H, acyl or alkyl, and z = O, H, H or H, OR2 where R2 = H or acyl, and salts of (I) are hypotensives and diuretics with positive inotropic and myotropic activity. (I) are prepd. by a multistage process using known reactions, from a 16 alpha, 17 alpha-epoxypregnane.</p> |