| 摘要 |
<p>D-homo-20-ketopregnanes of the formula <IMAGE> wherein R1 is hydrogen, fluorine, chlorine, bromine, alkyl, alkoxy, or azido; R2 is oxygen, <IMAGE> and R7 is hydrogen, lower alkyl, or acyl of up to 5 carbon atoms; R3 is hydrogen or methyl R4 is oxygen, two hydrogens, <IMAGE> R5 is hydrogen, hydroxy, alkoxy, azido, mercapto, thiocyano, cyano, dialkylamino, morpholino, thiomorpholino, or piperazino; R6 is methyl or ethyl; THE HYDROGEN ATOM IN THE 5-POSITION IS OF THE alpha - OR beta -CONFIGURATION; AND ACID ADDITION SALTS THEREOF, POSSESS NARCOTIC-ANESTHETIC ACTIVITY.</p> |
