| 摘要 |
2-Substituted-5-oxo-5H-dibenzo[a,d]cycloheptenes represented by the following formula: <IMAGE> where R' is hydrogen, alkyl having 1 to 12 carbon atoms, or <IMAGE> where n is an integer from 2 to 4, inclusive, and R4 and R5 are independently lower alkyl having 1 to 6 carbon atoms or together R4 and R5 and the nitrogen atom to which they are attached form a heterocyclic ring having 5 or 6 total ring atoms; one of R2 and R3 is hydrogen and the other is hydrogen, methyl, or ethyl, or together R2 and R3 are methylene; and the pharmaceutically acceptable salts thereof. The compounds have anti-inflammatory, analgesic, and antipyretic activities and, accordingly, are useful in the treatment of inflammation, pain and/or pyrexia.
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