| 摘要 |
Novel 2-[3'-(2-(3,4-dimethoxyphenyl)ethylamino)- 2'-hydroxypropoxy]-3-cyanopyridine of the formula <IMAGE> and its acid addition salts are prepared by hydrolysis of [3'-(2-(3,4-dimethoxyphenyl)ethyl)-2'-phenyloxazolidin-5'-yl]methoxy-3 -cyanopyridine. The compound and its salts are cardioselective beta receptor blockers having additional alpha receptor-blocking and hypertensive properties, by virtue of which they can be used in the treatment of the indications known for beta receptor blockers, e.g. angina pectoris and cardiac arrhythmias, in particular hypertension. |
