摘要 |
1470291 Immobilized enzymes W R GRACE & CO 1 Sept 1975 36001/75 Addition to 1429711 Heading C3H The invention of the parent Specification 1,429,711 which describes and claims foamable compositions comprising an isocyanate capped polyoxyethylene polyol is modified in that to the previously free isocyanate groups in a polyurethane molecule is chemically bound a residue of cellulose, pectinate, papain, bromelain, chymotrypsin, krypsin, ficin, lysozyme, lactose, amyloglucosidase, penicillin amidase, glucose isomerase, alpha-amylase, amino acid acylase, asparaginase, glucose oxidase, invertase, perioxidase, pullulanase, or rennin. Examples 1-10 describes the attachment of a selection of these enzymes to a polymer of ethylene glycol and toluene diisocyanate. Example 11 describes the conversion of penicillin G to 6-aminopenicillanic acid and Example 12 compares the efficacy of the product of the invention with those of the prior art. |