发明名称 DERIVES ARYLAMINO PYRIMIDINIQUES, LEUR PROCEDE DE PREPARATION ET LEUR APPLICATION EN APEUTIQUE
摘要 <p>Compounds of the formula WHEREIN Ar is phenyl or phenyl substituted by one or more halogens, by a trifluoromethyl or a methylenedioxy, by one or more methoxy, by an alkyl having one to 4 carbon atoms or by a dimethylamino, AND R is R1 -C-N ANGLE , PARALLEL OR2 or -O- R3 (CH2)n-N ANGLE , R4 or O C ANGLE OR5 wherein R1 and R2 each are hydrogen or alkyl of 1 to 4 carbon atoms, or R1 -N ANGLE R2 is pyrrolidino, morpholino, piperidino or piperazino N'-substituted by alkyl of 1 to 4 carbon atoms, or phenyl; R3 and R4 each are alkyl of 1 to 3 carbon atoms or R3 -N ANGLE R4 is morpholino, pyrrolidino, piperidino or hexamethyleneimino, n is an integer of 1 to 5; and R5 is alkyl of 1 to 4 carbon atoms, 2,3-dihydroxypropyl or 2,2-dimethyl dioxolan-4-yl methyl or hydroxycarbonylmethyl.</p>
申请公布号 CA1008074(A) 申请公布日期 1977.04.05
申请号 CA19740209631 申请日期 1974.09.18
申请人 DELALANDE S.A. 发明人 FAURAN, CLAUDE;BOURGERY, GUY;RAYNAUD, GUY;GOURET, CLAUDE
分类号 A61K31/505;C07D239/42;C07D401/10;C07D401/12;C07D403/10;C07D413/10 主分类号 A61K31/505
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