FORFARANDE FOR FRAMSTELLNING AV 2-HYDROXIMETYL-3-HYDROXI-6-(1-HYDROXI-2-T-BUTYLAMINOETYL)-PYRIDIN OCH MELLANPRODUKTER DERAV

摘要

1510075 Pyrido-dioxin derivative PFIZER Inc 19 Aug 1976 [3 Oct 1975] 34682/76 Heading C2C The novel maleate of a compound of formula is made by reacting the compound with maleic acid in ethyl acetate. The bronchodilator 2- hydroxymethyl - 3 - hydroxy - 6 - (1 - 2 - tbutylaminoethyl)-pyridine dihydrochloride is made by reacting the above maleate with excess hydrogen chloride in methanol solution.