摘要 |
1468758 Preparation of 2,6-dihydroxycineole CAMILLO CORVI SpA 30 May 1974 [12 June 1973 10 April 1974] 24090/74 Heading C2C Very pure 2,6-dihydroxy-cineole is prepared by reacting very pure sobrerol with a mineral or organic acid to give pinol, reacting the pinol with a peracid to give pinol epoxide of at least 98% purity and hydrolysing this in aqueous or aqueous/alcoholic solution using a mineral or organic acid. The processes may be illustrated by the reaction sequence: Pharmaceutical compositions having choleretic activity comprise the 2,6-dihydroxy-cineole prepared by the above process together with a suitable carrier or diluent. |