发明名称 2-METHYL-5-NITRO-1-(2-(HETEROARYLOXY)ETHYL)IMIDAZOLE
摘要 <p>1386210 2 - Methyl - 5 - nitro -1 - [2 - heteroaryloxy)ethyl]-imidazoles G D SEARLE & CO 11 Sept 1973 [11 Sept 1972] 42562/73 Heading C2C Novel compounds of Formula I: wherein R is a pyridyl or quinolyl (benzo-(b)- pyridyl) radical, optionally substituted by 1 to 3 halogen atoms, NO 2 groups and/or methyl groups are obtained by reacting a compound of Formula II: wherein A is a hydrogen atom or a radical of formula -CH 2 CH 2 X (wherein X is halogen, toluenesulphonyloxy or methanesulphonyloxy) with a compound of formula, B-R, wherein B is an alkali metal oxy group when A is -CH 2 CH 2 X or B is a radical of formula -O-CH 2 CH 2 X when A is a hydrogen atom. The imidazole derivatives of Formula I possess anti-microbial activity.</p>
申请公布号 CA1006873(A) 申请公布日期 1977.03.15
申请号 CA19730180630 申请日期 1973.09.10
申请人 G.D. SEARLE & CO. OF CANADA, LIMITED 发明人 KREIDER, EUNICE M.
分类号 C07D401/12 主分类号 C07D401/12
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