Radioactive iodine (125I) labeling of latex particles

摘要

The invention disclosed in this application is directed towards developing a radioiodination method which is applicable to the labeling of 2.02 micrometer ( mu m) and 0.37 micrometer ( mu m) diameter polyvinyltoluene latex particles that have been used as an immunoadsorbent. More particularly the overall method includes using an oxidation-reduction chemical reaction for tagging latex particles. Two methods are described. One, the hydrochloric acid method; and two, the nitric acid method.