摘要 |
<p>Novel carboxylic acids of the formula <IMAGE> I wherein Z is an aliphatic hydrocarbon chain selected from the group consisting of -(CH2)n- and -CH=CH-(CH2)n-2- where the double bond may be at any point in the chain, n is an integer from 5 to 10 and X, X1, X2 and X3 are individually selected from the group consisting of hydrogen, halogen, alkyl of 1 to 5 carbon atoms, alkoxy of 1 to 5 carbon atoms, alkylthio of 1 to 5 carbon atoms, CF3-, CF3O- and CF3S- and their non-toxic, pharmaceutically acceptable organic and inorganic salts and esters having analgesic and anti-inflammatory activity and their preparation.</p> |