| 摘要 |
<p>Compounds represented by general formula (I) and salts thereof and an antitumor agent comprising the same as the active ingredient: wherein R?1 and R2¿ each is hydrogen, halogeno, hydroxy, alkoxy, amino, alkylamino, aryl, or alkyl; R?3 and R4¿ each is hydrogen, halogeno, alkoxy, amino, alkylamino, aryl, or alkyl; R5 is hydrogen, alkyl, alkenyl, alkynyl, aryl, or arylalkyl; Q is amidino, cycloalkyl, phenyl, or monocyclic heterocycle (excluding pyrimidinyl bonded at the 2-position); G is a nitrogenous saturated heterocyclic structure represented by formula (1) wherein X1 is nitrogen or CH, which may contain a ketone moiety and may have one or more substituents on the ring; Z is phenyl or heterocycle which each may have one or more substituents and in which two substituents may be bonded to each other to form a fused dicyclic structure; and a substituent of Z and a substituent of G may be bonded to each other to form a fused tricyclic or tetracyclic structure together with G and Z.</p> |
