BENZODIAZEPINES AND PREPARATION THEREOF

摘要

1307475 Benzodiazepines SUMITOMO CHEMICAL CO Ltd 18 Aug 1971 [24 Aug 1970] 38796/71 Heading C2C Compounds of the general formula (R 1 = H, halogen, NO 2 C 1-4 alkoxy, CN, CF 3 ; R 2 =Py, R 5 R 6 Ph; R 5,6 =H, halogen, CF 3 , CN, C 1-4 alkyl; R 3,4 =H, C 1-4 alkyl; n= 1-4; cyclic ether group is 3-6 membered) and their acid addition salts, are prepared by introducing the 1-subatituent, optionally followed by salt formation. The above compounds are tranquillizers, sedatives, muscle relaxants, hypnotics and anticonvulsants, and may be administered in the form of pharmaceutical preparations containing them in association with a carrier. Reference has been directed by the Comptroller to Specification 972,968.