发明名称 1-%ARALKOXYPHENYL<-2 OR -3-%BIS-ARYLALKYLAMINO<-ALKANES
摘要 Compounds of the formula I which lower blood pressure and reduce the heart rate <IMAGE> are prepared, in which each of the symbols Ar1, Ar2 and Ar3 denotes a phenyl radical which is unsubstituted or substituted by one or more lower alkyl, lower alkoxy, trifluoromethyl, nitro, amino, mono-lower-alkylamino or di-lower-alkylamino, aminomethyl, mono-lower-alkylaminomethyl or di-lower-alkylaminomethyl groups or one or more halogen atoms, Ph is a phenylene radical which can optionally be substituted by one of the substituents mentioned for Ar1 and n is a number from 0 to 4, and each of the symbols m and p represents a number from 1 to 4, r is the number 1 or 2, and R1 is hydrogen or hydroxyl, and salts of these compounds. These are obtained by reduction of a compound which contains the group of the formula -CO-Cp-1H2p-2- in place of the group -CpH2pin the formula.
申请公布号 AU8362675(A) 申请公布日期 1977.02.10
申请号 AU19750083626 申请日期 1975.08.04
申请人 CIBA-GEIGY AG 发明人 JOHN E. FRANCIS
分类号 A61K31/135;A61K31/165;A61K31/195;A61K31/215;C07C45/00;C07C45/71;C07C67/00;C07C213/00;C07C225/16;C07C231/00;C07C233/76;C07C253/00;C07C255/58 主分类号 A61K31/135
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