发明名称 Matrix controlled transdermal system for stabile derivatives of ace inhibitors
摘要 In a transdermal therapeutic system (TTS) comprising an impermeable backing layer, one or more matrix layers and a removable backing layer, the matrix layers contain active agent(s) (A) consisting of a dicarboxylic acid angiotensin converting enzyme (ACE) inhibitor which has been derivatized to give a diester, a di-salt with base(s) or a mono-salt with acid(s). In a transdermal therapeutic system (TTS) comprising an impermeable backing layer, one or more matrix layers (where at least one of the layers is self-adhesive or a separate adhesive layer is provided) and a removable backing layer, the matrix layers contain active agent(s) (A) consisting of a dicarboxylic acid angiotensin converting enzyme (ACE) inhibitor which has been derivatized to give a diester, a di-salt with base(s) or a mono-salt with acid(s).
申请公布号 AU8197901(A) 申请公布日期 2002.01.21
申请号 AU20010081979 申请日期 2001.07.12
申请人 HEXAL AG 发明人 KARIN KLOKKERS;KAI-THOMAS KRAMER;WILFRIED FISCHER;ANNA SENDL-LANG
分类号 A61K9/70;A61K31/551;A61K31/675;A61K38/55;A61P9/12;A61P43/00 主分类号 A61K9/70
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