Process for preparing benzopyrano (2,3-d) triazoles

摘要

A process for preparing a compound of formula (I) <IMAGE> (I) wherein X phenyl optionally substituted by one halogen, C1-4 alkyl or C1-4 alkoxy; or pyridyl; R1 is hydrogen or C1-6 alkyl; and n is an integer of from 1 to 6; which process comprises, cyclizing a compound of formula (II): <IMAGE> (II) wherein X, R1 and n are as defined in relation to formula (I); Y is an hydroxy or an acid activating group and Rx is hydrogen or an N- protecting group and thereafter if desired carrying out one or more of the following steps: (i) removing any protecting group Rx, (ii) preparing a salt of the compound of formula (I).