PROCESS FOR PREPARING 3,4-DIFLUOROANILINE

摘要

2080596 9117138 PCTABS00008 A process for preparing 3,4-difluoroaniline comprising reacting 1-hydroxylamine-3-fluorobenzene with anhydrous hydrogen fluoride in the absence of oxygen. This compound is useful as a starting material for preparation of quinolone antibacterials. 3-Fluoro-1-hydroxylamine may be prepared by hydrogenating 3-fluoro-1-nitrobenzene.