A Disclosed is a method of therapeutically or prophylactically treating a pregnant mother for cocaine-induced fetal brain injury comprising administering a therapeutically or prophylactically effective amount of a cytochrome P450 inhibitor or prodrug thereof to the mother. Also disclosed is a method of screening for inhibitors of cocaine-induced fetal brain injury. Uses of compounds and compositions to manufacture a medicament for treating a pregnant mother for cocaine-induced fetal brain injury are further provided.
申请公布号
WO2008109724(A2)
申请公布日期
2008.09.12
申请号
WO2008US55998
申请日期
2008.03.06
申请人
GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES;LEE, CHUN-TING;FREED, WILLIAM, J.