| 摘要 |
NEW MATERIAL:Antibiotic substance TM-611 exhibiting the following physical and chemical properties as Na salt. Appearance, white acicular crystal; m.p., 203-205 deg.C; elemental analysis (%), C 62.97, H 8.69, Na 3.16; molecular weight, FABMS m/z 705 (M+H)<+>; molecular formula, C37H61O11Na; [alpha]D<27>=+29.2 deg. (c=0.5, CHCl3); solubility, insoluble in water and soluble in methanol, ethanol, acetone, ethyl acetate, benzene, chloroform and n-hexane; color reaction, negative to ninhydrin and FeCl3 reaction and positive to vanillin-sulfuric acid and iodine reaction; nature, weakly acidic in isolated state; etc. USE:An antibiotic substance exhibiting proliferation-inhibiting action against Gram-positive bacteria. Useful as pharmaceuticals, agricultural chemicals and feed additives. PREPARATION:Streptoverticillium olivoreticuli TM-611 (FERM P-8972) is cultured under aerobic condition. |
