<p>This invention relates to compounds of formula I RHN-Z-NH-(CH2)m-NH-Z-NHR (I). These compounds are particularly useful for treating a patient suffering from a neoplastic disease state. The compounds of formula I, may also be administered in a conjunctive therapy with a polyamine oxidase inhibitor.</p>
申请公布号
EP0378146(A2)
申请公布日期
1990.07.18
申请号
EP19900100303
申请日期
1990.01.08
申请人
MERRELL DOW PHARMACEUTICALS INC.
发明人
STEMERICK, DAVID M.;EDWARDS, MICHAEL L.;PRAKASH, NELLIKUNJA J.;BITONTI, ALAN J.;MCCANN, PETER P.;SJOERDSMA, ALBERT