| 摘要 |
<p>Crosslinking reagents glutaraldehyde and ethylene glycol diglycidyl ether have been used to bind epidermal growth factor ('EGF') to liposomal surfaces without utilizing the disulfide bridge linkage of EGF and, therefore, not adversely affecting the functionality of EGF. The crosslinking occurs through the amine residues offered by EGF and liposomes having phosphatidylethanolamine. The resulting EGF-modified liposomes offer potential as a microscopic drug delivery system.</p> |
