摘要 |
The invention relates to polyelectrolytes and their use in the separation of blood proteins. …<??>Blood coagulation factors such as Factor VIII are separated from admixture with other blood proteins without producing activation of said coagulation factor by contacting with a water-insoluble, cross-linked polyelectrolyte copolymer of (a) C2-18 unsaturated monomer and (b) C4-12 unsaturated polycarboxylic acid or anhydride, in which 2-100% of the carboxyl sites are substituted with amineimides and substantially all the free anhydrides are blocked with alkoxyalkylamine to form alkoxyalkylimide units. |