发明名称 |
POLYBASIC BACTERIAL EFFLUX PUMP INHIBITORS AND THERAPEUTIC USES THEREOF |
摘要 |
Disclosed are compounds having polybasic functionalities. The compounds inhibit bacterial efflux pump inhibitors and are used in combination with an anti-bacterial agent to treat or prevent bacterial infections. These combinations can be effective against bacterial infections that have developed resistance to anti-bacterial agents through an efflux pump mechanism.
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申请公布号 |
US2008318957(A1) |
申请公布日期 |
2008.12.25 |
申请号 |
US20080116172 |
申请日期 |
2008.05.06 |
申请人 |
MPEX PHARMACEUTICALS, INC. |
发明人 |
GLINKA TOMASZ;LOMOVSKAYA OLGA;BOSTIAN KEITH;WALLACE DAVID M. |
分类号 |
A61K31/47;A61K31/5375;A61P31/04;C07D215/38;C07D265/30 |
主分类号 |
A61K31/47 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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