发明名称 Compositions and methods relating to multimeric and oligomeric soluble fragments of the TWEAK receptor
摘要 The present invention provides methods and compositions relating to fusion proteins comprising multimeric soluble TWEAK receptor fragments and an oligomerization domain. Such fusion proteins are useful for antagonizing the TWEAK receptor and for treating diseases or conditions mediated by angiogenesis, such as solid tumors and inflammatory conditions.
申请公布号 US7482430(B2) 申请公布日期 2009.01.27
申请号 US20040898575 申请日期 2004.07.23
申请人 AMGEN INC. 发明人 WILEY STEVEN R.
分类号 A61K39/00;C07K14/00;C07K14/705 主分类号 A61K39/00
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