| 摘要 |
A compound having pharmaceutical activity, of the formula <IMG> (I) in which A is hydrogen or <IMG> where x is 0 or 1 to 4, R1 and R2 are each hydrogen or C1-9 alkyl and R3 is -CN, -COOH, tetrazolyl or <IMG> where R4 is optionally substituted phenyl, and -?-Y-Z- is selected from <IMG>, <IMG>, <IMG>, <IMG> and -?-N=N-where R5 and R6 are each hydrogen, C1-9 alkyl or <IMG> where x, R1, R2 and R3 are as defined above, and R7 is hydrogen, C1-4 alkyl or <IMG> where x is 1 to 4, and R1, R2 and R3 are as defined above; provided that when A is hydrogen at least one of R5, R6 and R7 is <IMG>, and provided that when -?-Y-Z- is <IMG>, A is <IMG> and x is 1 to 4 then R3 is <IMG>; and salts and esters thereof. G.1274 FF
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