发明名称 Process for the preparation of complexes of <sup>68</sup>Ga
摘要 A process for the preparation of complexes containing 68Ga wherein a buffer formic acid/formate in the presence of compounds capable to sequester metal cations is used in the complexion reaction.
申请公布号 US9375498(B2) 申请公布日期 2016.06.28
申请号 US201214237728 申请日期 2012.08.10
申请人 Advanced Accelerator Applications S.A. 发明人 Fugazza Lorenza;Filannino Maria Azzurra;Mariani Maurizio Franco
分类号 A61K51/04;A61K51/08;C07B59/00 主分类号 A61K51/04
代理机构 LeClairRyan, a Professional Corporation 代理人 LeClairRyan, a Professional Corporation
主权项 1. Process for the preparation of complexes of 68Ga wherein the complexing reaction between a chelator-functionalized molecule and 68Ga is carried out in a buffer formic acid/formate aqueous solution optionally in the presence of a compound capable of sequestering metal cations, wherein said compound able to sequester metal cations, if used, is added at the beginning of the complexing reaction.
地址 Saint Genis Pouilly FR