发明名称 Constitutive expression of costimulatory ligands on adoptively transferred T lymphocytes
摘要 The present invention provides immunoresponsive cells, including T cells, cytotoxic T cells, regulatory T cells, and Natural Killer (NK) cells, expressing at least one of an antigen recognizing receptor and a co-stimulatory ligand and methods of use therefore for the treatment of neoplasia and other pathologies where an increase in an antigen-specific immune response is desired. a b M, x2& I o KT 0tc IN~t WN w tz~ m W - ------ ymir '8 ,:Ma m MA- , r
申请公布号 AU2014203686(B2) 申请公布日期 2017.02.23
申请号 AU20140203686 申请日期 2014.07.04
申请人 Memorial Sloan-Kettering Cancer Center 发明人 Sadelain, Michel;Stephan, Matthias
分类号 C12N5/0783;A01N63/00 主分类号 C12N5/0783
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