SUBSTITUTED BENZALDEHYDE COMPOUNDS AND METHODS FOR THEIR USE IN INCREASING TISSUE OXYGENATION
摘要
[0242] Provided are substituted benzaldehydes and derivatives thereof that act as allosteric modulators of haemoglobin, methods and intermediates for their preparation, pharmaceutical compositions comprising the modulators, and methods for their use in treating disorders mediate by hemoglobin and disorders that would benefit from increased tissue oxygenation.
申请公布号
AU2016203755(A1)
申请公布日期
2016.06.23
申请号
AU20160203755
申请日期
2016.06.06
申请人
CYTOKINETICS, INC.;GLOBAL BLOOD THERAPEUTICS, INC.;THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
发明人
METCALF, BRIAN;CHUANG, CHIHYUAN;WARRINGTON, JEFFREY;JACOBSON, MATTHEW P.