摘要 |
Disclosed is a viral vector comprising
(a) a cDNA of a recombinant viral RNA
having at least the N gene, the X gene, the P gene, and the L gene of a Borna disease virus genome in the same order as that in the Borna disease virus genome, and
having a sequence in which a foreign gene is inserted into the untranslated region connected to the downstream of the open reading frame of the P gene,
(b) a DNA encoding a ribozyme, and
(c) a promoter sequence,
each being disposed in a position in which (b) is placed upstream and downstream of (a), and (a) and (b) are placed downstream of (c). |