| 摘要 |
Benzamides. (I; A = low molecular wt. mono- or dialkyl-amino; R = low molecular wt. alkyl or alkenyl; m <4; B = low molecular wt. alkyl or alkenyl; n = 1 or 2; X = amino, mono- or dialkylamino, alkyl or alkenyl) were prepd. by the reaction of 2,5-disubstituted benzoic acid(II) and H2N(CH2)n-A in the presence of anhydrous phosphoric acid. Thus, 2-methoxy 5-sulfamidobenzoic acid and N-ethyl 2-aminomethylpyrrolidine were reacted with anhydrous phosphoric acid in 150≦̸C to give N-(1-ethyl 2-pyrrolidylmethyl) 2-methoxy 5-sulfamidobenzamide in 67-9% yield.
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