| 摘要 |
Disclosed herein is a process for the synthesis of Bruton's tyrosine kinase inhibitors. This process includes treating tert-butyl-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3.4-d]pyrimidine-1-yl)piperidine-1-carboxylate with an acid, and then with a base with further combining with an acid chloride. |
