Local delivery of water-soluble or water-insoluble therapeutic agents to the surface of body lumens

摘要

LOCAL DELIVERY OF WATER-SOLUBLE OR WATER-INSOLUBLE THERAPEUTIC AGENTS TO THE SURFACE OF BODY LUMENS A catheter assembly (110) for insertion into the vasculature (220) comprising a balloon (112) having an outer surface; an amphiphilic polymer coating (116) disposed on the outer surface of the balloon (112), the amphiphilic polymer coating (116) comprising an amphiphilic polymer or co-polymer complexed with iodine, a hydrophobic therapeutic agent, and a plasticizer.