发明名称 Beta-lactam contng carboxylic acids salts-by cation - exchange pharmaceuticals
摘要 <p>The salts esp. penicillin and cephalosporin derivs, are prepd in high yield and purity under mild conditions by cation exchange. A trialkyl or triaryl silyl ester of the acid is reacted with R'OM, (where M is the cation required in the prodcut, and R' si acyl, alkyl, aryl, Si(alkyl)3 ro Si(aryl)3) in an aprotic solvent contg. insufficient H2O or alcohol for complete hydrolysis of the ester.</p>
申请公布号 DE2115542(A1) 申请公布日期 1972.10.05
申请号 DE19712115542 申请日期 1971.03.31
申请人 发明人
分类号 C07D499/00;C07D499/14;(IPC1-7):07D99/14 主分类号 C07D499/00
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