Procédé de préparation de nouvelles bases azotées contenant un radical naphtyle ou naphtyl-méthyle

摘要

(I) Amines n = 1 or 2 X = -COO- or -CH2O- R1 = tetrahydrofurfuryl when n = 2, propenyl when n = 1 and X = -COO-, or 3-4C unsatd. aliphatic gp. when n = 1 and X = -CH2O-. R2, R3 = lower alkyl or NR2R3 = piperidino, pyrrolidino or morpholino. When free base, X is -COO- and n = 2, R2 and R3 not both Et. (II) Acid-addn. and quat. ammonium salts of (I). (III) Alcohols:- Antispasmodics (10-40 times activity of papaverine); local anaesthetics; Acid-addn. salts have peripheral and coronary vasodilatory action; (III) are intermediates.