| 摘要 |
<p>1289132 Substituted 2-iminothiazolidin-4-ols SANDOZ Ltd 19 Nov 1969 [29 Nov 1908] 56523/69 Heading C2C The invention comprises compounds of formula and their acid addition salts, wherein R is C 1-4 alkyl, R<SP>1</SP> is H or C 1-3 alkyl, and each X is F or Cl, or one X may be H, and a process for making them by reacting together at 0-60‹ C. in an inert organic solvent, the appropriately substituted phenacyl chloride or bromide, and a N. N<SP>1</SP>-dialkylthionrea. Therapeutic compositions for oral administration comprise compounds of the above formula, which have anorexic, CNS-stimulant and antiinflammatory activity.</p> |
