Cis-oxalato(trans-L-1,2-cyclohexanediamine) Pt(II) complex having high optical purity and process of preparing same.

摘要

Disclosed is cis-oxalato(trans-l-1,2-cyclohexanediamine) Pt(II) complex having high optical purity and no toxicity and exhibiting anticancer performance, as shown in the below Formula. Cis-oxalato(trans-l-1,2-cyclohexanediamine) Pt(II) complex of the invention possesses high optical purity of 99.94 % or more e.e. and a melting point of 198.3 to 199.7 DEG C. The complex is synthesized employing as starting material trans-l-1,2-cyclohexamediamine or a derivative of the trans-l-1,2-cyclohexanediamine optically resoluted by means of a high performance liquid chromatography.