| 摘要 |
PROBLEM TO BE SOLVED: To provide a method for detecting and measuring a geographic atrophy of the eye by imaging the eye at a depth greater than the retinal pigment epithelium (RPE) at a plurality of locations of the eye, using optical coherence tomography (OCT).SOLUTION: Ratios of the intensities of a plurality of imaging signals of a retinal layer to the intensities of imaging signals of a sub-RPE layer are determined at each location. A plurality of representative values is determined based at least in part on the determined ratios. A map of the representative values is generated. Diseased areas are identified from the map. Contours and binary maps may be generated based on the identified diseased areas. The size and shape of the identified areas may be analyzed and monitored over a period of time to phenotype subjects and classify diseases.SELECTED DRAWING: Figure 8B |
