发明名称 INHIBITORS OF INFLUENZA VIRUSES REPLICATION
摘要 Methods of inhibiting the replication of influenza viruses in a biological sample or patient, of reducing the amount of influenza viruses in a biological sample or patient, and of treating influenza in a patient, comprises administering to said biological sample or patient an effective amount of a compound represented by Structural Formula (I): or a pharmaceutically acceptable salt thereof, wherein the values of Structural Formula (IA) are as described herein. A compound is represented by Structural Formula (IA) or a pharmaceutically acceptable salt thereof, wherein the values of Structural Formula (IA) are as described herein. A pharmaceutical composition comprises an effective amount of such a compound or pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier, adjuvant or vehicle.
申请公布号 HK1215675(A1) 申请公布日期 2016.09.09
申请号 HK20160103636 申请日期 2012.10.12
申请人 VERTEX PHARMACEUTICALS INCORPORATED 发明人 CHARIFSON, PAUL P;CLARK, MICHAEL, P. MP;BANDARAGE, UPUL, K. UK;BETHIEL, RANDY, S. RS;COURT, JOHN, J. JJ;DENG,HONGBO;DRUTU, IOANA I;DUFFY, JOHN, P. JP;FARMER, LUC L;GAO,HUAI;GU,WENXIN;JACOBS, DYLAN, H. DH;KENNEDY, JOSEPH, M. JM;LEDEBOER, MARK, W. MW;LEDFORD, BRIAN B;MALTAIS, FRANCOIS F;PEROLA, EMANUELE E;WANG, TIANSHENG;WANNAMAKER, M. WOODS MW;GERMANN, URSULA, A. UA;JONES, STEVEN S;JIANG,MIN;LIN,CHAO;ZHOU,YI;BYRN, RANDAL R;SALITURO, FRANCESCO, G. FG;ANN DAK-YEE KWONG
分类号 A61K;A61P;C07D 主分类号 A61K
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