摘要 |
PURPOSE:To obtain an antiviral agent containing a specific inhibiting substance as an active component, having low side actions and useful for the prevention and treatment of diseases caused by viruses having IRES such as HCV. CONSTITUTION:This antiviral agent contains, as an active component, a substance to inhibit the bonding of (A) a protein participating in the translation of a virus gene (preferably type-C hepatitis virus gene) by bonding to preferably Yn-Xm unit of the IRES region of the virus gene (Yn is an olig opyrimidine; Xm is a random nucleotide) and (B) the IRES region of the virus gene (preferably a compound forming a hybrid with the oligopyrimidine). |