发明名称 |
Protein kinase c inhibitors |
摘要 |
The present invention discloses compounds that are highly isozyme selective protein kinase C beta-1 and beta-2 isozyme inhibitors. Accordingly, the present invention provides a method of selectively inhibiting protein kinase C isozymes beta-1, and beta-2. As isozyme selective inhibitors of beta-1 and beta-2, the compounds are therapeutically useful in treating conditions associated with diabetes mellitus and its complications, as well as other disease states associated with an elevation of the beta-1 and beta-2 isozyme. |
申请公布号 |
AU1339895(A) |
申请公布日期 |
1995.07.10 |
申请号 |
AU19950013398 |
申请日期 |
1994.12.14 |
申请人 |
ELI LILLY AND COMPANY |
发明人 |
WILLIAM FRANCIS HEATH HEATH JR.;JOHN HAMPTON MCDONALD;MICHAEL PAAL;GERD RUTHER;THEO SCHOTTEN;WOLFGANG STENZEL |
分类号 |
C07D487/04;A61K31/40;A61K31/4025;A61K31/404;A61K31/437;A61K31/454;A61K31/7056;A61P3/10;A61P7/02;A61P9/00;A61P9/10;A61P9/12;A61P17/00;A61P17/06;A61P25/00;A61P25/28;A61P29/00;A61P35/00;A61P43/00;C07D401/14;C07D403/14;C07D405/14;C07D471/04;C07H15/26 |
主分类号 |
C07D487/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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