发明名称 |
Use of presenilin-1 for diagnosis of alzheimers disease |
摘要 |
The invention provides a method of diagnosing Alzheimer's disease. The method utilizes presenilin-1, whose level is found to be substantially decreased in Alzheimer's patients. Included in the invention are diagnostic kits for Alzheimer's disease and methods of screening for effective therapeutics for the disease. The invention also provides a method of studying the function and regulation of presenilin-1 in brain by the use of primate retinoblastoma cells.
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申请公布号 |
US5985581(A) |
申请公布日期 |
1999.11.16 |
申请号 |
US19970896176 |
申请日期 |
1997.07.17 |
申请人 |
THE MCLEAN HOSPITAL CORPORATION |
发明人 |
NIXON, RALPH A.;CATALDO, ANNE M.;KAO, BENJAMIN H.;MATHEWS, PAUL M. |
分类号 |
C07K16/18;G01N33/68;(IPC1-7):G01N33/53;G01N33/48;G01N33/543 |
主分类号 |
C07K16/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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