| 发明名称 |
NICOTINAMIDE DERIVATIVES USEFUL AS PDE4 INHIBITORS |
| 摘要 |
The invention relates to nicotinamide derivatives of formula (1) and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. The nicotinamide derivatives according to the present invention are phosphodiesterase-4 inhibitors and are useful in numerous diseases, disorders and ( conditions, in particular inflammatory, allergic, respiratory diseases, disorders and conditions, as well as wounds. |
| 申请公布号 |
EA008939(B1) |
申请公布日期 |
2007.10.26 |
| 申请号 |
EA20040000892 |
申请日期 |
2003.02.03 |
| 申请人 |
PFIZER INC. |
发明人 |
BAILY SIMON;GAUTIER ELISABETH, COLETTE, LOUISE;HENDERSON ALAN, JOHN;MAGEE THOMAS, VICTOR;MARFAT ANTHONY;MATHIAS JOHN, PAUL;MCLEOD DALE, GORDON;MONAGHAN SANDRA, MARINA;STAMMEN BLANDA, LUZIA, CHRISTA |
| 分类号 |
A61K31/455;A61K31/44;A61K31/443;A61K31/4433;A61K31/4545;A61K31/46;A61K31/537;A61K45/06;A61P1/00;A61P1/04;A61P1/16;A61P1/18;A61P3/10;A61P7/06;A61P9/12;A61P11/00;A61P11/06;A61P11/08;A61P13/12;A61P17/02;A61P17/04;A61P17/06;A61P19/00;A61P19/02;A61P19/10;A61P25/00;A61P25/14;A61P25/16;A61P25/24;A61P25/28;A61P25/30;A61P27/02;A61P29/00;A61P31/16;A61P31/22;A61P35/00;A61P37/00;A61P37/02;A61P43/00;C07D213/82;C07D401/12;C07D405/12;C07D451/04;C07D451/10 |
主分类号 |
A61K31/455 |
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