| 发明名称 |
METHODS AND COMPOSITIONS FOR EXPANDING LONG-TERM HEMATOPOIETIC STEM CELL POPULATIONS |
| 摘要 |
The invention generally features compositions and methods for expanding long term hematopoietic stem cells (HSCs) in a population of cells. In particular, the invention relates to a method of expanding long term HSCs by culturing an initial population of HSCs with macrophages that promote self-renewal of long term HSCs. The expanded cell population provides a source of cells for therapeutic treatments utilizing HSC transplantation. |
| 申请公布号 |
US2016158288(A1) |
申请公布日期 |
2016.06.09 |
| 申请号 |
US201414903548 |
申请日期 |
2014.07.14 |
| 申请人 |
ZHOU Daohong;LUO Yi;SHAO Lijian;FENG Wei;CHANG Jianhui;THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS |
发明人 |
Zhou Daohong;Luo Yi;Shao Lijian;Feng Wei;Chang Jianhui |
| 分类号 |
A61K35/28;C12N5/0789 |
主分类号 |
A61K35/28 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. (canceled) |
| 地址 |
Little Rock AR US |
