摘要 |
Cmpds. of formulae (I), (II) and (III):- where X = H, Cl or F R' = OH or acyloxy R2 = OH or acyloxy or with R' is alkylidenedioxy R3 = H, alpha- or beta-CH3 or with R' is alkylidenedioxy R4 = H, Cl or F R5 = OH or Cl;R4 and R5 are same when R5 = Cl R7 = H or CH3 R8 = H, C6H5, ClC6H4, FC6H;, CH3OC6H4, CH3C6H4 Z = single or double bond, single when R7 is H. Corticoid, antiinflammatory and progestational agents useful in treatment of allergy, menstrual disorders, and fertility. Some anti-androgenic, anti-oestrogenic and antigonadotropic effects are present. |