Novel opiold peptides for the treatment of pain and use thereof

摘要

FIELD: organic chemistry, peptides. SUBSTANCE: invention relates to opioid peptides of the formula (I): X-R1-R2-R3-Q-R4-N(Y)Z and its analogues where X is H or C1-6-alkyl; Y, Z - H, cyclic aralkyl and C1-6-alkyl; R1 - tyrosyl residue, 2',6'-dimethyltyrosyl residue or their analogue; R3, R4 - aromatic amino acid residue (other values see p. 1 of the invention claim). Peptides show peripheral analgetic effect. EFFECT: valuable pharmacological property of peptides. 21 cl, 1 tbl, 6 dwg, 3 ex