| 发明名称 |
METHOD FOR DESIGNING DNA-BINDING PROTEINS OF THE ZINC-FINGER CLASS |
| 摘要 |
The invention is directed to the design of DNA-binding proteins (DBP's) with capabilities of binding to any predetermined target double-stranded DNA sequence. Disclosed are the rules for design of the proteins; an algorithm for screening for the optimal DBP's; a computer system employing the rules and the algorithm; general formulae encompassing the proteins; and methods of use of the proteins.
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| 申请公布号 |
CA2321088(A1) |
申请公布日期 |
1999.08.26 |
| 申请号 |
CA19992321088 |
申请日期 |
1999.02.19 |
| 申请人 |
GENOME DYNAMICS, INC. |
发明人 |
MICHAELS, GEORGE S.;FELDMANN, RICHARD J.;MIKELSAAR, RAIK-HIIO |
| 分类号 |
C12N15/09;C07B61/00;C07K1/00;C07K14/00;C07K14/47;G06F17/50;(IPC1-7):C07K1/00 |
主分类号 |
C12N15/09 |
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