发明名称 MANIFESTATION INHIBITOR CONTAINING ANTI-SENSE OLIGONUCLEOTIDE DERIVATIVE AGAINST HUMAN INTERLEUKIN-6 RECEPTOR
摘要 PURPOSE:To obtain the subject inhibitor useful as a human interleukin-6 activity inhibitor, containing an anti-sense oligonucleotide derivative against human interleukin-6 receptor (human IL-6R) as an active ingredient. CONSTITUTION:This manifestation inhibitor contains, as active ingredient, an anti-sense oligonucleotide derivative hydrodized with the region of a consecutive 9 to 30 base sequence containing a translation-initiating codon for mRNA coding human IL-6R.
申请公布号 JPH0797337(A) 申请公布日期 1995.04.11
申请号 JP19930300338 申请日期 1993.11.30
申请人 CHUGAI PHARMACEUT CO LTD 发明人 FUJITA JUN
分类号 A61K45/00;C07K7/08;C07K14/52;C07K14/54;C07K14/705 主分类号 A61K45/00
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