Identification and use of target genes for control of plant parasitic nematodes

摘要

The invention relates to identifying and evaluating target coding sequences for control of plant parasitic nematodes by inhibiting one or more biological functions, and their use. The invention provides methods and compositions for identification of such sequences and for the control of a plant-parasitic nematode population. By feeding one or more recombinant double stranded RNA molecules provided by the invention to the nematode, a reduction in disease may be obtained through suppression of nematode gene expression. The invention is also directed to methods for making transgenic plants that express the double stranded RNA molecules, and the plant cells and plants obtained thereby.

主权项

1. A method for controlling a plant-parasitic nematode population comprising providing an agent comprising a double stranded ribonucleotide sequence that functions upon being taken up by the nematode to inhibit a biological function of Kin-2 within said nematode, wherein the agent comprises at least 21 contiguous nucleotides of a nucleotide sequence selected from the group consisting of SEQ ID NO:506, SEQ ID NO:787, SEQ ID NO:1921 and SEQ ID NO:1926.