NOVEL PYRIDINE DERIVATIVE AND MEDICAMENT CONTAINING THE SAME AS AN EFFECTIVE INGREDIENT

摘要

Pyridine derivatives represented by general formula (1) and salts thereof, and medicines containing the same as the active ingredient, such as a cytokine production inhibitor, wherein R1 and R2 represent each H, alkyl, cycloalkyl, hydroxyalkyl, optionally substituted alkoxyalkyl, carboxyalkyl, alkoxycarbonylalkyl, optionally substituted aralkyl, phenacyl or acyl; R3 represents alkyl, optionally substituted phenyl, heteroaryl or cyclic amino; and X represents O or a combination of OH with H. These compounds have potent and highly specific and safe immune function regulating effects capable of suppressing excessive production of specified cytokines in various immunologic diseases.